EverspanITP-Validated Compounds
by NIA Interventions Testing Program
Compounds that extended lifespan in genetically diverse mice through the National Institute on Aging's rigorous Interventions Testing Program – the gold standard for pre-human longevity compound testing.
6
Interventions
B
Avg. Evidence
$326–$1340
/month (stack)
Varies
Practitioner Est.
Intervention Stack
17-alpha-Estradiol
Research suggests this estrogen stereoisomer may extend lifespan in male mice while avoiding feminizing effects.
Acarbose
An alpha-glucosidase inhibitor showing potential longevity benefits through metabolic modulation and caloric restriction mimetics.
Low-Dose Aspirin
Well-studied anti-platelet therapy with extensive evidence for cardiovascular protection and potential longevity benefits.
Metformin
Diabetes medication showing promise for aging and healthspan extension in research studies
Rapamycin (Sirolimus)
An mTOR inhibitor showing lifespan extension in animal models, now under investigation for human aging.